An unparalleled approach for MALDI mass spectrometry imaging of metabolites in FFPE tissue

Formalin-fixed, paraffin-embedded (FFPE) tissue samples possess great potential to provide metabolic insights into physiologically normal, predisposed and pathological processes. Building on established protocols and applications expertise in mass spectrometry imaging of metabolites in FFPE tissues, multiple biomolecules can be analyzed label-free with high spatial resolution in the context of tissue morphology. Theratype’s molecular imaging approach permits reliable high-throughput in situ metabolomics-based biomarker discovery and validation for research purposes and clinical application using prospective and retrospective FFPE sample collections.

Application note: MALDI mass spectrometry imaging of metabolites in FFPE tissue