SPACiAL: A new method for immunophenotype-guided imaging mass spectrometry

Prade, V. M. and Kunzke, T. et al. (2020). De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry. Molecular Metabolism, DOI: 10.1016/j.molmet.2020.01.017.

A new method for immunophenotype-guided imaging mass spectrometry allows accurate, objective and time-efficient annotation of specific cell types within a tissue section. This automatic pipeline represents an important step towards the analysis of large-scale clinical cohort studies for artificial intelligence guided diagnostics, biomarker discovery or therapy prediction.